An engineered E. coli strain sustains intratumoral nitric oxide production to boost effectiveness of tumor immunotherapy

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This is a summary of: Xu, S. et al. Sustained nitric oxide production by engineered E. coli remodels the tumor microenvironment and potentiates immunotherapy. Nat. Biotechnol. https://doi.org/10.1038/s41587-026-03054-y (2026).