An open-source photobleacher for fluorescence imaging of large pigment-rich tissues

Proceedings of the National Academy of Sciences, Volume 122, Issue 38, September 2025. <br/>SignificancePhotobleaching is an effective technique for quenching endogenous pigments, enabling multiplexed fluorescence imaging of pigment-rich tissues, such as postmortem human samples. While many photobleaching strategies have been proposed, there is …