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An unusual Co–S bond links B12 chaperones in an interprotein complex
https://www.profitableratecpm.com/f4ffsdxe?key=39b1ebce72f3758345b2155c98e6709c
Proceedings of the National Academy of Sciences, Volume 122, Issue 39, September 2025. <br/>SignificanceApproximately a third of all proteins require metal cofactors that are often delivered by dedicated chaperones. The B12trafficking proteins MMACHC and MMADHC exhibit low affinity for each other in the absence of the cofactor, but form a tight …



