Antagonism by the type VI secretion system of Bacteroides fragilis is controlled by a TetR family regulator and released small molecule

Proceedings of the National Academy of Sciences, Volume 123, Issue 15, April 2026. <br/>SignificanceThere are numerous external and intrinsic signals that dictate when bacteria become aggressive and when they activate their defensive systems. Here,Bacteroides fragilisstrains with a GA3 T6SS are shown to release a small molecule that acts …