ARP2/3 complex mediates the neuropathology of PTEN-deficient human neural cells downstream of mTORC1 and mTORC2 hyperactivation
https://www.profitableratecpm.com/f4ffsdxe?key=39b1ebce72f3758345b2155c98e6709c
Proceedings of the National Academy of Sciences, Volume 123, Number 7, February 2026.
SignificanceMutations in the phosphatase and tensin homolog (PTEN) gene cause neurodevelopmental disorders characterized by brain overgrowth, autism, and epilepsy. These conditions are associated with hyperactivation of the mechanistic target of rapamycin (…
