Broad beta-CoV immunity and transmission blockade by a single-dose live-attenuated vaccine with atypical codon usage

https://www.profitableratecpm.com/f4ffsdxe?key=39b1ebce72f3758345b2155c98e6709c

Proceedings of the National Academy of Sciences, Volume 123, Number 4, January 2026.
Significance We report a rationally designed live attenuated beta-coronavirus (cb1) vaccine with modified codon usage bias. CB1 is a highly attenuated but immunologically potent vaccine capable of eliciting systemic and mucosal immune responses, …

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