Grin2b 3’UTR is necessary for synaptic plasticity and spatial learning

Proceedings of the National Academy of Sciences, Volume 123, Number 8, February 2026.
SignificanceMany studies have dissected the plasticity and memory of NMDA receptor proteins, but the untranslated regions (UTRs) of their mRNAs remain largely unexplored. We present a mouse model that harbors a deleted Grin2b3’UTR, one of the three longest in…