Integrating spatial omics and single-cell mass spectrometry imaging reveals tumor–host metabolic interplay in hepatocellular carcinoma

Proceedings of the National Academy of Sciences, Volume 122, Issue 31, August 2025. <br/>SignificanceVarious cellular populations in tumors continuously engage in highly active metabolic exchanges. However, the heterogeneous tumor microenvironment (TME) makes it challenging to characterize cell-specific metabolic interactions and their …