Mixed-mobility supported lipid bilayers uncover the role of immobilized ICAM1 on T cell activation and immune synapse organization

Proceedings of the National Academy of Sciences, Volume 123, Number 11, March 2026.
Significance This research explores how the mobility of a key immune ligand, intercellular adhesion molecule 1 (ICAM1), influences T cell activation. T cells have a receptor that binds specifically to ICAM1, triggering events that contribute to T cell development…