Molecular basis for substrate recognition and transport of mammalian taurine transporters

Proceedings of the National Academy of Sciences, Volume 122, Issue 27, July 2025. <br/>SignificanceThe taurine transporter, TAUT, actively transports taurine using ion gradients across the cell membrane. Dysfunction of TAUT has been associated with retinal degeneration, cardiomyopathy, and poor outcomes in multiple cancers. Moreover, recent …