NEDD4L induces mitochondrial dysfunction and neurodegeneration by promoting LIPT2 degradation in Huntington’s disease
https://www.profitableratecpm.com/f4ffsdxe?key=39b1ebce72f3758345b2155c98e6709c
Proceedings of the National Academy of Sciences, Volume 122, number 29, July 2025.
The significant disturbance in protein protein protein is associated with neurodegeneration in Huntington (HD) disease. The E3 ligases are responsible for maintaining the homeostasis of mitochondrial proteins, while this process remains poorly understood …
