PI31 expression is neuroprotective in a mouse model of early-onset parkinsonism

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Proceedings of the National Academy of Sciences, Volume 122, number 38, September 2025.
significant infbxo7 / park15 early parkinsonism in human patients. Using the KO models of conditional mice at the same time, we will demonstrate that the deficiency in FBXO7 causes PI31 destabilization, a transport of altered synaptic proteasome and …

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