Podocin oligomers regulate the ordering of nephrin chains, providing the molecular basis of NPHS2 interallelic interactions
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Proceedings of the National Academy of Sciences, Volume 123, Number 16, April 2026.
ImportanceThe kidney filters blood through a specialized barrier formed by proteins such as nephrin, the precise spacing of which determines the size of the filtration pores. Inherited kidney diseases that disrupt this barrier cause a massive leak of proteins into…
