Rewiring STAT signaling from the cell surface with Trikine immunotherapeutics | Science

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Rewiring STAT signaling from the cell surface with Trikine immunotherapeutics | Science
Cytokines dimerize two receptor chains to activate Janus kinases and signal transducers and activators of transcription (STAT) transcription factors that regulate immune cells, but they have therapeutic responsibilities. We designed “Trikines” to constrain cis…

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