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SARS-CoV-2 mutant spectrum complexity is an epidemiologically evolvable trait

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Proceedings of the National Academy of Sciences, Volume 122, Issue 39, September 2025. <br/>SignificanceA mutant spectrum shrinkage of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) was observed as the COVID-19 pandemic advanced. This suggests that virus from late COVID-19 waves has fewer alternative mutational pathways available …

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