SARS-CoV-2 nucleocapsid protein directly prevents cGAS–DNA recognition through competitive binding

Proceedings of the National Academy of Sciences, Volume 122, Issue 26, July 2025. <br/>SignificanceSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a master of immune evasion, employing multiple mechanisms to subvert host immune responses. While its ability to block RNA-sensing pathways is well established, how SARS-CoV-2 …