Stress-dependent growth in breast cancer arises from a mechano-osmotic coupling and cell-sizing checkpoint

Proceedings of the National Academy of Sciences, Volume 123, Number 10, March 2026.
ImportanceMechanical control of tumor cell proliferation mirrors healthy tissue, in which cells stop dividing under confinement and compressive stress. Although this behavior is evident at the tissue scale, the underlying biomechanisms at the cellular scale that…