Structural and dynamic basis of indirect apoptosis inhibition by Bcl-xL: A case study with Bid

Proceedings of the National Academy of Sciences, Volume 123, Issue 20, May 2026. <br/>SignificanceProgrammed cell death, or apoptosis, is a fundamental process that eliminates damaged cells. However, cancer cells often evade this process by overexpressing antiapoptotic Bcl-2 family proteins, which neutralize their proapoptotic …