Structural insights into SetA-mediated Rab1 glucosylation and PI3P-guided localization during early Legionella infection

Proceedings of the National Academy of Sciences, Volume 123, Issue 13, March 2026. <br/>SignificanceLegionella pneumophilaremodels host membrane trafficking to establish a replication-permissive niche, yet the molecular basis of this process is not fully understood. Here, we elucidate the structural basis by which the effector SetA couples …