Structural insights into the substrate uptake and inhibition of the human creatine transporter (hCRT)

Proceedings of the National Academy of Sciences, Volume 122, number 36, September 2025.
Significant is well known as an energy booster for muscles, but it also plays a key role in brain function and has recently been recognized as a neurotransmitter. Its transport in cells is based on a protein called a transporter of human creatine (…