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Teaching machines to design molecular switches

https://www.profitableratecpm.com/f4ffsdxe?key=39b1ebce72f3758345b2155c98e6709c

In biology, many RNA molecules act as sophisticated microscopic machines. Among them, riboswitches function as tiny biological sensors, changing their 3D shape upon binding to a specific metabolite. This shape-change acts as a switch, often turning a downstream gene “on” or “off.” The ability to design artificial switches from scratch would hold immense promise for synthetic biology, drug design, and new diagnostic tools. However, designing a sequence that can stably fold into two different shapes and switch between them is an extremely difficult challenge.

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