The dawn of in vivo immune cell engineering in oncology

June, CH, O’Connor, RS, Kawalekar, OU, Ghassemi, S. and Milone, MC Science 3591361-1365 (2018).

Article CAS PubMed Google Scholar

Müller, F. et al. N.Engl. J.Med. 390687-700 (2024).

Article PubMed Google Scholar

Mikhael, J., Fowler, J. and Shah, N. JCO Oncol. Practice. 18800-807 (2022).

Article PubMed Google Scholar

Morris, EC, Neelapu, SS, Giavridis, T. and Sadelain, M. Nat. Reverend Immunol. 2285-96 (2022).

Article CAS PubMed Google Scholar

Ottaviano, G. and Qasim, W. Leukemia 391325-1333 (2025).

Article PubMed PubMed Central Google Scholar

Uslu, U. and June, CH Nat. Biotechnology. 43506-515 (2025).

Article CAS PubMed Google Scholar

Escobar, G., Berger, TR and Maus, MV Cell Rep. Med. https://doi.org/10.1016/j.xcrm.2025.102353 (2025).

Article PubMed PubMed Central Google Scholar

Diorio, C., Teachey, DT and Grupp, SA Nat. Reverend Clin. Oncol. 2210-27 (2025).

Article CAS PubMed Google Scholar

Bot, A. et al. Nat Rev. https://doi.org/10.1038/s41573-025-01291-5 (2025).

Article PubMed Google Scholar

Xu, J. et al. Lancet 406228-231 (2025).

Article CAS PubMed Google Scholar

Wang, Q. et al. N.Engl. J.Med. 3931542-1544 (2025).

Article PubMed Google Scholar

Nicolai, CJ et al. Blood 144977-987 (2024).

Article CAS PubMed PubMed Central Google Scholar

Hunter, TL et al. Science 3881311-1317 (2025).

Article CAS PubMed Google Scholar

Andorko, JI et al. Mol. There. 334937-4952 (2025).

Article CAS PubMed Google Scholar

Kantarjian, H. et al. N.Engl. J.Med. 376836-847 (2017).

Article CAS PubMed PubMed Central Google Scholar

Onuora, S. Nat. Reverend Rheumatol. 20667 (2024).

Article CAS PubMed Google Scholar

Philipp, N. et al. Blood 1401104-1118 (2022).

Article CAS PubMed PubMed Central Google Scholar

Urits, I. et al. Neurol. There. 9301-315 (2020).

Article PubMed PubMed Central Google Scholar

Chen, DS and Mellman, I. Immunity 391–10 (2013).

Article PubMed Google Scholar

Nagarsheth, New Brunswick et al. Nat. Med. 27419-425 (2021).

Article CAS PubMed PubMed Central Google Scholar

Cheloni, G. et al. Nat. Common. 164819 (2025).

Article CAS PubMed PubMed Central Google Scholar

Scholler, N. et al. Nat. Med. 281872-1882 (2022).

Article CAS PubMed PubMed Central Google Scholar

Chen, P.-H. et al. JCI Overview 5e134612 (2020).

Article PubMed PubMed Central Google Scholar

Locke, FL et al. Blood Adv. 44898-4911 (2020).

Article PubMed PubMed Central Google Scholar

Bot, A., Dudley, M., Shelley, D. and Sotiropoulou, PA Nat. Rev. https://doi.org/10.1038/d41573-025-00191-y (2025).

Article PubMed Google Scholar