The locus coeruleus maintains core body temperature and protects against hypothermia during dexmedetomidine-induced sedation

Proceedings of the National Academy of Sciences, Volume 122, Number 41, October 2025.
ImportanceDexmedetomidine (DEX), a sedative widely used in intensive care, induces a state of wakefulness resembling non-rapid eye movement (NREM) sleep and lowers body temperature. For some patients, even slight decreases in body temperature during…