Structural basis for substrate specificity and MSMEG_0435-0436 binding by the mycobacterial long-chain acyl-CoA carboxylase complex

Proceedings of the National Academy of Sciences, Volume 123, Issue 12, March 2026. <br/>SignificanceMycobacterium tuberculosisand related pathogens possess an unusual cell wall, rich in mycolic acid, that protects them from antibiotics and the host immune system. This study presents the structure of the mycobacterial long-chain acyl-CoA …