A ribosomally synthesized and posttranslationally modified peptide with ADP-ribosylation

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Proceedings of the National Academy of Sciences, Volume 123, Number 7, February 2026.
ImportanceADP-ribosylation of adenosine diphosphate has not yet been extensively studied in the biosynthesis of natural products. Here we report minviopeptin, an ADP-ribosyltransferase MicD-modified triceptide, marking a significant breakthrough as…

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